Today we are going to discuss about Multiple Sclerosis Symptoms & Treatment. Multiple sclerosis is a serious and progressive disease. It is difficult to diagnose at early stage disease and mostly occurs in young people & it’s most common in females.
Moreover it is related to multiple auto immune diseases and it is categorized in auto immune disorders. It has multiple triggers such as viruses, bacteria and some environmental factors.
It is more common in certain age groups and races. Sometimes it behaves very abnormal so it is necessary to diagnose it at very early stage. so, timely new things are adding into it and number of patients is increasing with awareness. Multiple Sclerosis types, symptoms, diagnosis & treatment.
- brain stem
- cerebellum, which includes movement and balance control
- optic sensors
- white matter in other regions of the brain
It has basically four types. First relapse, then remid and relaptic remidding occurs. Second is primary progressive and third is secondary progressive. Fourth is recurrent. First is of two types, one is benign and other is clinical isolating syndrome.
Four types of Multiple Sclerosis:
Rewind-Reminding MS (RRMS). This is the most common form of multiple sclerosis. People who initially diagnosed with RRMS are about 85% with MS. People with RRMS have intermittent periods called backslides, explosions or climbs, when new symptoms appear
Secondary-Progressive MS (SPMS). In SPMS, symptoms worsen over time, or occur without recurrence and remission. Most people diagnosed with RRMS will switch to SPMS sometime3
MS-Progressive MS (PPMS). This type of MS is very rare, occurring in about 10% of people with MS. Worsening symptoms from the beginning, with no relapses or remission is PPMS.
Progressive-Relapsing MS (PRMS). In a rare form of MS (5%), a steadily worsening disease state from the start, with acute relapses but no remission, with or without recovery is PRMS.
In clinical isolating syndrome patients initially experience pain in his eyes and dim vision which is progressive. First they think it’s may be due to stress/anxiety OR our over study to be the cause. But as it is progressive with time patients are at the risk of blindness. Sometimes it is normal clinical symptoms which get normalized within 2 to 3 weeks.
It affects different parts of body, some patients have visual symptoms others have cerebral disorders because of which they have difficulty in standing and posture because of which they cannot touch the object asked. As sometimes autonomic nervous system gets evolved so they might have weak bladder. Sometimes patients come with question about weak bladder that is unable to pass urine.
Sometimes when multiple sclerosis progresses it effects certain parts of brain in different patients it has different symptoms outcomes such as visual problems of one or both eyes, posture problems, numbness and sometimes causes twitching on face. These are the alarming symptoms to swiftly get to physician consultation.
Diagnosis and Precautions:
Nero physician has main objective to diagnose the type of disorder patient has. For that purpose MRI is most important to test. This tells whether it is present at one sight or multiple, either it is in brain stem or some where else. It has particular signs and symptoms. Moreover different auto immune diseases are difficult to differentiate so this is difficult part and diagnosed with correlation with family history, gender and profile testing.
It has various side effects such as depression, posture problems, and fatigue along with frustration. Not only the white matter get involved with time but grey matters also get involved with the time. Such patients also get epilepsy with time.
For malignant form, proper treatment is important to treat patient timely with shifting the patient to ICU. Critical testing and monitoring is essential for such patients to check up on either electrolyte imbalance is occurring or not, kidney health is Ok, chest infection should be avoided. Because such issues aggravate.
Educating the patient and family is very crucial. Its treatment is very expensive, it don’t have hundred percent cure. Medicines can relieve 50% of the disease and their side effect has another topic. New medicines has side effects on immune system along with fungal and some other infections. Parents and patients should have awareness related to everything and doctor should educate them to large extent.
There are various treatments for MS available today that have been shown to reduce the frequency of relapses and to delay the progression of the disease. There are several ways in which these therapies can be taken. Some therapies use injections – either subcutaneous (subcutaneous) or intramuscular (intramuscular) – while others are administered intravenously (infusion) or orally (orally).
Interferon beta: This is an injectable drug which is used for treatment of relaspsing MS. For initial clinical and MRI findings associated with MS, certain products of beta interferon can also be used. Depending on the medication, beta interferon injections can be subcutaneous or intravenous and dosage may vary from one day to another once a week.
Glatiramer acetate is given as an underground daily injection in the treatment of relapsing MS. Patients who have experienced the first episode of the clinic and have had MRI-related MRI findings are treated with it.
Fingolimod is a once-daily oral capsule shown in the treatment of recurrent forms of MS to reduce the frequency of clinical increase and delay the accumulation of physical disability.
Teriflunomide is a simultaneous oral tablet used for the treatment of patients with recurrent forms of multiple sclerosis
Dimethyl fumarate is an oral capsule taken twice a day. People who have relapsing forms of MS use this for their treatment.
Mitoxantrone is a chemotherapeutic agent for the treatment of recurrent and recurrent MS, recurrent MS or progressive MS, and is used to reduce neurologic impairment and / or increased clinical frequency. It is injected intravenously once every three months
Natalizumab is an injectable drug prescribed to patients with MS who develop rapidly or with a high incidence despite using alternative therapies for MS are prescribed this injectionable drug. It is administered once every four weeks.